Optimizing Cognitive Remediation Outcomes in Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder with Psychotic Symptoms (FORECAST)

Joshua Woolley M.D. and the Bonding & Attunement in Neuropsychiatric Disorders (BAND) Lab are currently conducting a research study to investigate the feasibility of remote neuroplasticity-based cognitive remediation.  This study is interested in how computerized cognitive training helps people with schizophrenia lessen their symptoms and learn new ways of thinking and problem solving.  In this study, participants complete 70 hours of cognitive training exercises from the convenience of their own homes using study-provided iPads instead of having to regularly travel to the study site.

Participants will be actively involved in the research study for approximately 20 weeks, with follow up appointments after 6, 12, and 24 months following completion of computer training.  There are two modules of computer training.  The first module is 8 weeks (40 sessions) with each session lasting about one hour.  The second module is 6 weeks (30 sessions) with each session lasting about one hour.   In order to see the greatest benefits, participants would ideally be able to dedicate at least 5 hours a week to training (1 hour per day, five days per week).

Participants will need to come to the San Francisco VA Medical Center for several testing days, including before the start of cognitive training, after completion of module 1, after completion of module 2, and for follow up appointments.  These testing appointments will consist of interviews, computerized tests, questionnaires, and fMRI & MEG scans.  Participants are compensated for all assessment appointments, brain scans, and completed iPad training sessions. 

At the end of the study, participants could potentially earn over $1000.

Eligible Participants Should:

  • Have a diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic symptoms
  • Be in good general health
  • Be an outpatient on stable medication
  • Speak English as their first language
  • Have no metal in their body
  • Be between the pages of 18 and 65 


If you think you would be a good fit for this study, please contact:

Win Huynh

Recruitment Coordinator