Here are some programs and people that we are affiliated with. Feel free to explore!
UCSF Part Program
The staff at the PART program is dedicated to learning about how to identify individuals in the early phase of psychosis in the hope of delaying or preventing psychosis in individuals at clinical high risk and improving the course of psychosis in individuals who have already been diagnosed. Our team is comprised of staff and faculty at the University of California, San Francisco and the San Francisco Veterans Affairs Medical Center.
Dr. Aoife O'Donovan, PhD
People who experience traumatic or enduring psychological stress are more likely to develop age-related diseases such as cardiovascular disease, cancer and neurodegenerative disorders and to die at a younger age than people who do not experience such psychological stress. My research is focused on revealing how such psychological stress “gets under the skin” and more precisely “into cells” to increase risk for age-related diseases. The goal of this work is to identify the psychological and biological factors that account for the faster rate of biological aging observed in people experiencing psychological stress, and ultimately to drive the development of targeted interventions to reduce such negative effects of stress. To this end, I am currently focused on examining the effects of specific kinds of psychological stress on indices and mechanisms of biological including telomere shortening, oxidative stress and inflammatory activity.
Dr. Sophia Vinogradov, MD
For the past 10 years, the Vinogradov Lab has focused on the design, implementation, and evaluation of neuroscience-informed computerized cognitive training exercises that target the cognitive deficits of schizophrenia. For example, we have shown that 50 hours (10 weeks) of training of basic auditory processing and auditory/verbal working memory results in significant improvements in untrained measures of verbal learning and memory and general cognition in adults with schizophrenia. We have also shown that this form of training is associated with quality of life improvements months after training is completed; and that it “normalizes” brain activation patterns during basic auditory processing as well as higher-order complex cognitions. We have investigated serum biomarkers associated with the intervention and have demonstrated that medication-induced anticholinergic burden adversely affects patients’ cognitive gains after training. Though in its early stages, this work is paving the way for an entirely new treatment approach for schizophrenia and other neuropsychiatric illnesses.
Dr. Wendy Berry Mendes, PhD
Wendy Berry Mendes has served as a mentor for Dr. Woolley.
In the Emotion, Health, and Psychophysiology Lab we study embodiment -- how the mind influences the body, and the reciprocal, how bodily changes influence thoughts, emotions, and intentions. For example, we study how emotions are experienced differently along the developmental trajectory, how aging influences risk perceptions and risk taking, how decisions are influenced by acute and chronic stress, and how people manage and attempt to control their racial biases and how those regulatory attempts often fail resulting in revealing greater racial bias.
Dr. Daniel H. Mathalon, MD/PhD
Welcome to the Brain Imaging and EEG Laboratory. BIEEGL is a clinical and cognitive neuroscience laboratory dedicated to understanding schizophrenia. The scientists at BIEEGL use advanced imagining techniques to study the brain structure and function of patients diagnosed with schizophrenia. People without schizophrenia who meet other research criteria may participate as part of a control group to compare the brains of people with schizophrenia and healthy people to learn about the causes of psychotic symptoms.
BIEEGL is a University of California, San Francisco research laboratory located at the San Francisco VA Medical Center. The lab also conducts research at the University of California, San Francisco and has an additional lab at the Butler Building of the Langley Porter Psychiatric Institute.