Below you'll find information about our ongoing studies. Please let us know if you are interested in participating. The contact information for each study is listed along with the study descriptions below. If you would like to participate in a study, but do not know which you qualify for, please call our study staff at (415) 221-4810 ext 24117, or email [email protected]. Click here to learn about our Completed Studies.
Enhanced Cohesion Oxytocin Study (ECHO)
Psychobiological Assessment and Enhancement of Team Cohesion and Psychological Resilience using a Virtual Team Cohesion Test
The purpose of this study is to examine the interaction oxytocin has on group cohesion and group dynamics in Reserve Officer Training Corps (ROTC) cadets and healthy civilians. Click here for the background of this project!
PTSD Oxytocin Project (POP)
The effects of oxytocin on social ability, alcohol approach bias, and startle hyperreactivity in veterans with alcohol use disorder and post traumatic stress disorder
This study aims to examine the therapeutic effectiveness of oxytocin administration in people with a duel diagnosis of post traumatic stress disorder (PTSD) and alcohol use disorder (AUD). Among patients with PTSD, those who also have AUD are more likely to relapse, be hospitalized, and have decreased social functioning. Oxytocin is the only known medication that targets social deficits, addictive behavior, and autonomic hyperreactivity and anxiety, suggesting that its use could reduce some of the symptoms seen in PTSD and AUD.
Psychosis Oxytocin Research Quest (PORQ)
Effects of Oxytocin on Social Cognition in Psychosis-Spectrum Disorders
The purpose of this study is to test the effects of oxytocin on the abilities of patients with schizophrenia and schizoaffective disorder to engage socially with others. These psychosis-spectrum disorders are associated with significant social cognitive and behavioral deficits that are strongly associated with quality of life and functional outcomes. Intranasal administration of oxytocin has powerful prosocial effects and may be an effective adjunctive treatment for improving social deficits in this patient population.
We are currently looking for both healthy controls and patients for this study. We are currently looking for individuals between the ages of 18 and 65 who have a current diagnosis of schizophrenia, schizophreniform or schizoaffective disorder to participate in this study as patients. If you would like to participate as a patient, please call (415) 221-4810 ext 24117 or email [email protected] for more information.
Resolving Psychological Stress (REPS 2.0)
Using a Mobile Application as an Add-on Treatment for Post Traumatic Stress Disorder (PTSD) and Alcohol Use Disorder (AUD)
This study aims to evaluate the effectiveness of a smartphone application as an add-on treatment for people with comorbid PTSD and AUD. The application is intended to modify attentional bias to threat. Attentional bias training has shown some promise in reducing symptoms similar to those experienced by people with PTSD. Our goal is to develop a convenient, easy to use, and cost-effective treatment for PTSD.
We are currently looking for individuals to participate in this study. If you have or believe you have both PTSD and AUD and are interested in participating in our study, give our team a call at (415) 221-4810 ext. 25164 or send an email to [email protected] with "REPS 2.0 PTSD Study" in the subject.
Oxytocin HIV Meth Study (OHM)
This study aims to examine the effects of oxytocin on methamphetamine use disorder in men who have sex with men. Oxytocin has been shown to have anti-addiction effects in animal models of substance dependence and holds potential as a treatment for methamphetamine use disorder when combined with psychosocial therapy.
Stimulant Oxytocin Study (SOS)
This study aims to examine the effects of oxytocin on stimulant use disorder and co-occuring opioid use disorder in Veteran populations.
We are currently looking for Veterans with cocaine use disorder who are enrolled as a patient at the SFVAMC Opioid Treatment Program. Participants must speak English fluently and be at least 18 years old.
Psilocybin for AIDS Survivors Study (PASS)
Psilocybin-assisted Group Therapy for Demoralization in Long-term AIDS Survivors
The purpose of this study is to determine whether psilocybin, the psychadelic compound found in “magic mushrooms,” can be used with group therapy to improve the mental health of long-term AIDS survivors. Click here to read about a recently published article about the PASS study!
We will soon be looking to recruit gay-identified men over the age of 50 who are living with HIV. The participant must speak English fluently. If you would like to participate in PASS as a patient, please email [email protected] or call 415-476-7432.
MDMA for PTSD Study
This Phase 3 study is centered around understanding the underlying mechanisms through which MDMA coupled with psychotherapy may be useful for the treatment of PTSD.